THE EFFECTS OF THE COMBINATION OF IRON70 AND CYCLOPHOSPHAMIDE ON ORAL GLUCOSE TOLERANCE TEST IN WISTAR MALE ALBINO RATS

ABSTRACT

Chemotherapy is a term use in the 21st century to describe the treatment or the inhibition of abnormal cells or the growth of an infectious agent in the system of an organism. These infectious agent might be benign or malignant tumors or a microbe like a bacteria or virus. To investigate the effects of these cyclophosphamide and imidacloprid when combined on blood glucose level of an organism precisely male albino rats is the aim and the base line of this study or research program. The animals where kept for two weeks for acclamatisation, base line information collected like weight ranging from 150g to 200g. these animals were divided into four groups treated as follows, group one (Distilled water10mg/kg/bwt), group two (CP 5mg/kg/bwt), group three (CP5mg/kg/bwt)+ iron 70(16.1mg/kg/dl), group four iron70(16.1mg/kg/bwt) , each group containing four animal. Treatment was done for 21days, after which their oral blood glucose were measured at 0, 30, 60, 90,120 and 240 minutes. It was found that a part of group one all other groups had a rise in glucose level, this rise is as a results of the treatment that each group had received which has actually affected that their glucose regulatory mechanism. As a result these combined or individual chemicals should be apply with appropriate prescription by a qualify medical personnel and a continuous follow up.
KEY WORDS; cyclophosphamide, imidacloprid, diabetes, TH1 (T-helper cells)

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